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1

Cholesterol is required for Leishmania donovani infection: implications in leishmaniasis

Thomas J. Pucadyil, Poonam Tewary, Rentala Madhubala, Amitabha Chattopadhyay

Journal:

Molecular and Biochemical Parasitology

Année:

2004

Langue:

english

Fichier:

PDF, 127 KB

english, 2004

2

Leishmaniasis: Current Status of Vaccine Development

Sukumaran, Bindu, Madhubala, Rentala

Journal:

Current Molecular Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 275 KB

english, 2004

3

Leishmania parasites are inhibited by the benzoxaborole AN2690 targeting leucyl-tRNA synthetase

Manhas, Reetika, Tandon, Smriti, Sen, Shib Sankar, Tiwari, Neha, Munde, Manoj, Madhubala, Rentala

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2018

Langue:

english

Fichier:

PDF, 6.11 MB

english, 2018

4

A Plant like Cytochrome P450 Subfamily CYP710C1 Gene in Leishmania donovani Encodes Sterol C-22 Desaturase and its Over-expression Leads to Resistance to Amphotericin B

Bansal, Ruby, Sen, Shib Sankar, Muthuswami, Rohini, Madhubala, Rentala, Nakhasi, Hira L.

Journal:

PLoS Neglected Tropical Diseases

Année:

2019

Langue:

english

Fichier:

PDF, 7.53 MB

english, 2019

5

Vaccination with Leishmania soluble antigen and immunostimulatory oligodeoxynucleotides induces specific immunity and protection against Leishmania donovani infection

Poonam Tewary, Jayesh Mehta, Bindu Sukumaran, Rentala Madhubala

Journal:

FEMS Immunology & Medical Microbiology

Année:

2004

Langue:

english

Fichier:

PDF, 293 KB

english, 2004

6

Inhibition of glutathione synthesis as a chemotherapeutic strategy for leishmaniasis

Preeti Kapoor, Monika Sachdev, Rentala Madhubala

Journal:

Tropical Medicine & International Health

Année:

2000

Langue:

english

Fichier:

PDF, 137 KB

english, 2000

7

Inhibition of ornithine decarboxylase and S-adenosylmethionine decarboxylase synthesis by antisense oligodeoxynucleotides

Rentala Madhubala, Anthony E. Pegg

Journal:

Molecular and Cellular Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 374 KB

english, 1992

8

TheLeishmaniagenome project: new insights into gene organization and function

Peter J. Myler, Stephen M. Beverley, Angela K. Cruz, Deborah E. Dobson, Alasdair C. Ivens, Paul D. McDonagh, Rentala Madhubala, Santiago Martinez-Calvillo, Jeronimo C. Ruiz, Alka Saxena, Ellen Sisk, S

Journal:

Medical Microbiology and Immunology

Année:

2001

Langue:

english

Fichier:

PDF, 92 KB

english, 2001

9

Novel convenient synthesis of biologically active esters of hydroxylamine

Maxim A. Khomutov, Swati Mandal, Janne Weisell, Neiha Saxena, Alina R. Simonian, Jouko Vepsalainen, Rentala Madhubala, Sergey N. Kochetkov

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 311 KB

english, 2010

10

Drug targets inLeishmania

Bhavna Chawla, Rentala Madhubala

Journal:

Journal of Parasitic Diseases

Année:

2010

Langue:

english

Fichier:

PDF, 488 KB

english, 2010

11

Combined Action of Inhibitors of S-Adenosylmethionine Decarboxylase with an Antimalarial Drug, Chloroquine, on Plasmodium falciparum

BHAGWAN DAS, RASHMI GUPTA, RENTALA MADHUBALA

Journal:

Journal of Eukaryotic Microbiology

Année:

1997

Langue:

english

Fichier:

PDF, 580 KB

english, 1997

12

Expression of biopterin transporter (BT1) protein in Leishmania

Vandana S Dole, Peter J Myler, Kenneth D Stuart, Rentala Madhubala

Journal:

FEMS Microbiology Letters

Année:

2002

Langue:

english

Fichier:

PDF, 309 KB

english, 2002

13

Corrigendum to: ‘Vaccination with Leishmania soluble antigen and immunostimulatory oligodeoxynucleotides induces specific immunity and protection against Leishmania donovani infection’: [FEMS Immunology and Medical Microbiology 42 (2004) 241–248]

Poonam Tewary, Jayesh Pandya, Bindu Sukumaran, Rentala Madhubala

Journal:

FEMS Immunology & Medical Microbiology

Année:

2005

Fichier:

PDF, 191 KB

2005

14

Leishmania lipophosphoglycan activates the transcription factor activating protein 1 in J774A.1 macrophages through the extracellular signal-related kinase (ERK) and p38 mitogen-activated protein kinase

Sridevi Balaraman, Vandana K. Singh, Poonam Tewary, Rentala Madhubala

Journal:

Molecular and Biochemical Parasitology

Année:

2005

Langue:

english

Fichier:

PDF, 426 KB

english, 2005

15

Roles for mitochondria in pentamidine susceptibility and resistance in Leishmania donovani

Angana Mukherjee, Prasad K. Padmanabhan, Mayurbhai H. Sahani, Michael Peter Barrett, Rentala Madhubala

Journal:

Molecular and Biochemical Parasitology

Année:

2006

Langue:

english

Fichier:

PDF, 612 KB

english, 2006

16

Paromomycin: Uptake and resistance in Leishmania donovani

Anupam Jhingran, Bhavna Chawla, Shailendra Saxena, Michael Peter Barrett, Rentala Madhubala

Journal:

Molecular and Biochemical Parasitology

Année:

2009

Langue:

english

Fichier:

PDF, 207 KB

english, 2009

17

Leishmania donovani encodes a functional enzyme involved in vitamin c biosynthesis: Arabino-1,4-lactone oxidase

Neha Biyani, Rentala Madhubala

Journal:

Molecular and Biochemical Parasitology

Année:

2011

Langue:

english

Fichier:

PDF, 797 KB

english, 2011

18

Differential expression of proteins in antimony-susceptible and -resistant isolates of Leishmania donovani

Neha Biyani, Alok Kumar Singh, Swati Mandal, Bhavna Chawla, Rentala Madhubala

Journal:

Molecular and Biochemical Parasitology

Année:

2011

Langue:

english

Fichier:

PDF, 747 KB

english, 2011

19

The Leishmania donovani LD1 locus gene ORFG encodes a biopterin transporter (BT1)

Craig Lemley, Shaofeng Yan, Vandana S Dole, Rentala Madhubala, Mark L Cunningham, Stephen M Beverley, Peter J Myler, Kenneth D Stuart

Journal:

Molecular and Biochemical Parasitology

Année:

1999

Langue:

english

Fichier:

PDF, 196 KB

english, 1999

20

Leishmania donovani induces interferon regulatory factor in murine macrophages: a host defense response

Sridevi Balaraman, Poonam Tewary, Vandana Km Singh, Rentala Madhubala

Journal:

Biochemical and Biophysical Research Communications

Année:

2004

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2004

21

Leishmania donovani activates nuclear transcription factor-κB in macrophages through reactive oxygen intermediates

Vandana Km. Singh, Sridevi Balaraman, Poonam Tewary, Rentala Madhubala

Journal:

Biochemical and Biophysical Research Communications

Année:

2004

Langue:

english

Fichier:

PDF, 3.75 MB

english, 2004

22

Glyoxalase I from Leishmania donovani: A potential target for anti-parasite drug

Prasad K. Padmanabhan, Angana Mukherjee, Sushma Singh, Swati Chattopadhyaya, Venkataraman S. Gowri, Peter J. Myler, Narayanaswamy Srinivasan, Rentala Madhubala

Journal:

Biochemical and Biophysical Research Communications

Année:

2005

Langue:

english

Fichier:

PDF, 648 KB

english, 2005

23

The sterol-binding antibiotic nystatin inhibits entry of non-opsonized Leishmania donovani into macrophages

Poonam Tewary, Kumari Veena, Thomas J. Pucadyil, Amitabha Chattopadhyay, Rentala Madhubala

Journal:

Biochemical and Biophysical Research Communications

Année:

2006

Langue:

english

Fichier:

PDF, 217 KB

english, 2006

24

Novel agmatine analogue, γ-guanidinooxypropylamine (GAPA) efficiently inhibits proliferation of Leishmania donovani by depletion of intracellular polyamine levels

Sushma Singh, Anupam Jhingran, Ankur Sharma, Alina R. Simonian, Pasi Soininen, Jouko Vepsalainen, Alex R. Khomutov, Rentala Madhubala

Journal:

Biochemical and Biophysical Research Communications

Année:

2008

Langue:

english

Fichier:

PDF, 450 KB

english, 2008

25

Characterization and localization of ORFF gene from the LD1 locus of Leishmania donovani

Manju Jain, Rentala Madhubala

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 796 KB

english, 2008

26

A glutathione-specific aldose reductase of Leishmania donovani and its potential implications for methylglyoxal detoxification pathway

Jyoti Rath, V.S. Gowri, Swati C. Chauhan, Prasad K. Padmanabhan, N. Srinivasan, Rentala Madhubala

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2009

27

Immunostimulatory oligodeoxynucleotides are potent enhancers of protective immunity in mice immunized with recombinant ORFF leishmanial antigen

Poonam Tewary, Bindu Sukumaran, Shailendra Saxena, Rentala Madhubala

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 165 KB

english, 2004

28

Co-administration of IL-12 DNA with rORFF antigen confers long-term protective immunity against experimental visceral leishmaniaisis

Poonam Tewary, Shailendra Saxena, Rentala Madhubala

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 316 KB

english, 2006

29

Immunization with recombinant LD1 antigens protects against experimental leishmaniasis

Vandana S Dole, V.Samuel Raj, Anirban Ghosh, Rentala Madhubala, Peter J Myler, Kenneth D Stuart

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 228 KB

english, 2000

30

Vaccination with DNA encoding ORFF antigen confers protective immunity in mice infected with Leishmania donovani

Bindu Sukumaran, Poonam Tewary, Shailendra Saxena, Rentala Madhubala

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 203 KB

english, 2003

31

Expression of biopterin transporter (BT1) protein in Leishmania

Vandana S Dole, Peter J Myler, Kenneth D Stuart, Rentala Madhubala

Journal:

FEMS Microbiology Letters

Année:

2002

Langue:

english

Fichier:

PDF, 312 KB

english, 2002

32

Regulation of mammalian S-Adenosylmethionine decarboxylase

Anthony E. Pegg, Takaaki Kameji, Akira Shirahata, Bruce Stanley, Rentala Madhubala, Antti Pajunen

Journal:

Advances in Enzyme Regulation

Année:

1988

Langue:

english

Fichier:

PDF, 792 KB

english, 1988

33

Inhibition of Ornithine Decarboxylase Activity by Follicle Stimulating Hormone in Primary Culture of Rat Sertoli Cells

RENTALA MADHUBALA, SANKARARAMAN SHUBHADA, ANNA STEINBERGER, YU-HUI TSAI

Journal:

Journal of Andrology

Année:

1987

Langue:

english

Fichier:

PDF, 810 KB

english, 1987

34

Quantitative proteomic profiling of the promastigotes and the intracellular amastigotes of Leishmania donovani isolates identifies novel proteins having a role in Leishmania differentiation and intracellular survival

Neha Biyani, Rentala Madhubala

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2012

Langue:

english

Fichier:

PDF, 600 KB

english, 2012

35

Corrigendum to: ‘Vaccination with Leishmania soluble antigen and immunostimulatory oligodeoxynucleotides induces specific immunity and protection against Leishmania donovani infection’ : [FEMS Immunology and Medical Microbiology 42 (2004) 241–248]

Poonam Tewary, Jayesh Pandya, Bindu Sukumaran, Rentala Madhubala

Journal:

FEMS Immunology & Medical Microbiology

Année:

2005

Fichier:

PDF, 191 KB

2005

36

Unique posttranslational modifications in eukaryotic translation factors and their roles in protozoan parasite viability and pathogenesis

Mittal, Nimisha, Subramanian, Gowri, Bütikofer, Peter, Madhubala, Rentala

Journal:

Molecular and Biochemical Parasitology

Année:

2013

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2013

37

Unusual domain architecture of aminoacyl tRNA synthetases and their paralogs fromLeishmania major

V S Gowri, Indira Ghosh, Amit Sharma, Rentala Madhubala

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 957 KB

english, 2012

38

Visceral and post-Kala-Azar dermal leishmaniasis isolates show significant difference in their in vitro drug susceptibility pattern

Jyotsna Mishra, Rentala Madhubala, Sarman Singh

Journal:

Parasitology Research

Année:

2013

Langue:

english

Fichier:

PDF, 299 KB

english, 2013

39

A quantitative proteomic screen to identify potential drug resistance mechanism in α-difluoromethylornithine (DFMO) resistant Leishmania donovani

Singh, Alok Kumar, Roberts, Sigrid, Ullman, Buddy, Madhubala, Rentala

Journal:

Journal of Proteomics

Année:

2014

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2014

40

Deletion of Vitamin C biosynthesis enzyme, Arabino-1, 4-lactone oxidase in L eishmania donovani results in increased pro-inflammatory responses from host immune cells

Manhas, Reetika, Anand, Sneha, Tripathi, Pankaj, Madhubala, Rentala

Journal:

Molecular Microbiology

Année:

2014

Langue:

english

Fichier:

PDF, 572 KB

english, 2014

41

Leishmania genome analysis and high-throughput immunological screening identifies tuzin as a novel vaccine candidate against visceral leishmaniasis

Lakshmi, Bhavana Sethu, Wang, Ruobing, Madhubala, Rentala

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2014

42

Cryptosporidium parvum has an active hypusine biosynthesis pathway

Mittal, Nimisha, Morada, Marie, Tripathi, Pankaj, Gowri, V.S., Mandal, Swati, Quirch, Alison, Park, Myung Hee, Yarlett, Nigel, Madhubala, Rentala

Journal:

Molecular and Biochemical Parasitology

Année:

2014

Langue:

english

Fichier:

PDF, 2.62 MB

english, 2014

43

Isolation and Characterization of Human Breast Adenocarcinoma Cells Made Resistant to α -Difluoromethylornithine

Das, Bhagwan, Vig, Monika, Khurana, Kamal K., Madhubala, Rentala

Journal:

Cancer Investigation

Année:

2000

Langue:

english

Fichier:

PDF, 597 KB

english, 2000

44

Proteomic-Based Approach To Gain Insight into Reprogramming of THP-1 Cells Exposed to Leishmania donovani over an Early Temporal Window

Singh, Alok Kumar, Pandey, Rajeev Kumar, Siqueira-Neto, Jair Lage, Kwon, Yong-Jun, Freitas-Junior, Lucio H., Shaha, Chandrima, Madhubala, Rentala, Appleton, J. A.

Journal:

Infection and Immunity

Année:

2015

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2015

45

Identification and Characterization of a Novel Deoxyhypusine Synthase in Leishmania donovani

Chawla, Bhavna, Jhingran, Anupam, Singh, Sushma, Tyagi, Nidhi, Park, Myung Hee, Srinivasan, N., Roberts, Sigrid C., Madhubala, Rentala

Journal:

Journal of Biological Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 4.80 MB

english, 2010

46

A Heterologous Prime‐Boost Vaccination Regimen Using ORFF DNA and Recombinant ORFF Protein Confers Protective Immunity against Experimental Visceral Leishmaniasis

Tewary, Poonam, Jain, Manju, Sahani, Mayurbhai H., Saxena, Shailendra, Madhubala, Rentala

Journal:

The Journal of Infectious Diseases

Année:

2005

Langue:

english

Fichier:

PDF, 157 KB

english, 2005

47

Biochemical, Mutational and In Silico Structural Evidence for a Functional Dimeric Form of the Ornithine Decarboxylase from Entamoeba histolytica

Preeti,, Tapas, Satya, Kumar, Pravindra, Madhubala, Rentala, Tomar, Shailly, Valenzuela, Jesus G.

Journal:

PLoS Neglected Tropical Diseases

Année:

2012

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2012

48

EFFECT OF LEISHMANIA DONOVANI LIPOPHOSPHOGLYCAN ON ORNITHINE DECARBOXYLASE ACTIVITY IN MACROPHAGES

Kapoor, P., Raj, V. Samuel, Saxena, Shailendra, Balaraman, Sridevi, Madhubala, Rentala

Journal:

Journal of Parasitology

Année:

2001

Langue:

english

Fichier:

PDF, 105 KB

english, 2001

49

Genetically Engineered Ascorbic acid-deficient Live Mutants of Leishmania donovani induce long lasting Protective Immunity against Visceral Leishmaniasis

Anand, Sneha, Madhubala, Rentala

Journal:

Scientific Reports

Année:

2015

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2015

50

Leishmania donovani Encodes a Functional Selenocysteinyl-tRNA Synthase

Manhas, Reetika, Gowri, Venkatraman Subramanian, Madhubala, Rentala

Journal:

Journal of Biological Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 7.25 MB

english, 2016